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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4eb99c5dc16f1acba602180e52a9f32fc559cae16c3d3bc9391f77fa97c9905d' 
  AND token = 'AKIL03Dqo4UlwvhAlC1VNQWuXuFfKPJki50q4e9eTws=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}