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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1050bd74a3f2e21591a269b53663711ec4b144e6c443316113473ac075fdc9a' 
  AND token = 'm+53NKxxSFnQREjjBuyiD9r+baN09NY/LbY/M2YtbUU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}