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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9de0c8984adc0bfe7faddd26ed78e4981c97f2217f6fa3629657090be74a0bf' 
  AND token = 'NcTJsn+wuue1GhoUGwO9TGPUUXS3Um3UA+yEfknnmmw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}