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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ffe5a1783c2bcfebb4e164fb83720d9c5673401c904a7f28f035239a221ca229' 
  AND token = '0LuIJ5CzcwIpCMIaMFpRqCIdsoxSCOJsDOhEgdgjR1I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}