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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5722c8e510c68d2c0685d972b44e2906a0bce3aea49e267698654b656a0006b' 
  AND token = 'x2hFOx/328YG87jIvHYhuYCsKCnxY2Mc0RpAq8TCAOo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}