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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28609aba52f5e7e55d6d1cf2c2819c14012b211caf10e1f4d7de1a6aab2bb7a0' 
  AND token = '7T5fh75901zfKzDs/KlJF80GiOhGoQBd2h285oTPeDE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}