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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54052d1b459e7143bedef94d380a6f4c4750a3ac222f7141d00ad824c7bbf855' 
  AND token = 'l/3L/fzIzOlataLdT/X2T+Zp0LbIjOgP6vqxN8Fi9Y0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}