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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae3d002b6629a6898ac3acc0ca1c4100c1a6513152cdc52e8e3637930d72c03d' 
  AND token = 'LxGS3TA4b8xhvf3dC+lsKF0tW+DzKzh0XiWNN/lkPu0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}