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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef625c216afff71b9795e9b5b6c3aed657cd8cc775bda555cafbeae579429f21' 
  AND token = 'lekwjf+LH3TfcTN9JfkWZKRRbtONKRbgvnMRhdLM1nY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}