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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a599cd83e8b2c08cf90697d4c78c7174193934c033b26b74230b73ac78319c3' 
  AND token = '3QiU6MElhNUWJxKEhSwnb6MDj1nVciQu6KOilFs/Y0c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}