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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43b9a30f235e95f8520bf3ace47aa8e5704fa5302941df072dfd4bc49adfd584' 
  AND token = 'n24+fiHKj+qIM9EUIkPdaA171696PwEA1OF4LRiiBVI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}