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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '869c009ebc1e7fed31d8eef4c354eefb706fd9d9d7214a29c347f7945681e44f' 
  AND token = '4Mg8g/PdeQ3CmtP/BSDoEWd8hoUKInzNr08O2pdG+Dg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}