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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11afc98ac8fd1e830c5bc39f55576978db75f3ac56e4079c3a9515be88d6dfb4' 
  AND token = 'fk7NcdTFwORLHD9dgNqgYBtSh/pZ9xX8b/tDOEo5xis=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}