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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f98e9e421b91c566b32c6911c8943c3018add0c02293f5a36c34e8ec9d01883b' 
  AND token = 'pND158aSKMWIL0yImoOJtXHDzUudPdBCs8WMVybbA+0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}