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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '95a41d694a08dbbb46cd4f663e404d84c74e21b4f2a23bbcbb46cc9ec25483f0' 
  AND token = 'CWkpqOZgl3LI5FXS+kHAMSk+ccnPI/M80yggiKcy/rg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}