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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8bc41c340d6a126e6876daea645dda072f4ad734da5250c5db7f277c341a5c82' 
  AND token = 'Xd0cUDD/D6xu7C/oI0En7G37/doqq+RR7uynosHF1Rk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}