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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a3aef4d4565461cf220fb65b926134fb8e99460cbbca7306ca429ddebacda35e' 
  AND token = '+pCOe6b0lEfkv/Lyn/BCa5pSzp3gkCjQOa1vSo7T7LQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}