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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f8678c9f6c90e5f768b12d4d4397cec91978672333b62a298a95619e720bcd6' 
  AND token = 'sXWNF1D4Hn4qhTeZhtk1ZjrPxFhMKo1PxfTq9X5BsGo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}