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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd84e38e1c629e27d92d000a85320da1df392d899f8fe632c21f260f0c8088d4f' 
  AND token = 'vnC1gtEYsvG2IWg96W+L0TVTVS9YvPgzAiFzQEX7gR4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}