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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34e732e20082f4ab58cb26b8ac77fd87714ac0ebc67ea01bb14271a2b35e5995' 
  AND token = 'j8hWjEP+tU6ta3cAtNtW8wjEHF55OqPW5j1V5Bvr6G8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}