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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bf4fd3e6e7eb505f1f90c702aebdb0728a87569f9c78501ee006da9cbd0043d3' 
  AND token = 'zwJQFDXaH0ZPp3zqwntfsSxant3drxeB43KEzizctyg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}