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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d86f124fb8ec6b06281068565ca1d5cd308d7db8cca94d8c83f50a473261022' 
  AND token = '16szkwqLih1K+Jv1M3/h4qHiHPqye65kT1eF3oHmPN0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}