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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d938933e01da095a2ea11ca38861ca456f54e497fb9e7103f1edcf8e3986009' 
  AND token = 'xI0gvAFglqKiEbZy/a/9w86Hg4KmXdQsXHLoVy8aTDo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}