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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '854e490ccc1b724bff655f2fb68a8e6bc359b7a2df074fff3e7a899d1e428b9b' 
  AND token = 'fZMvRvUVUtQyP1edl++ADrIYmmG5DdNrpyLmzY2l7vE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}