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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3922b9edc49fffbb1a31aa0463b08aa099058d193c53d8e9a165ad857c097232' 
  AND token = 'Swx9Ha7gI7B3d4CGB9ht481CdUkIIqotYxGoSQyzcc8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}