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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ee243b0df764c86e2f9abc2c880621b36216a1d5dcc68e8209169c1e93b4339' 
  AND token = 'Xa9NX6Y11QTQpEeo3vvgFgS39lSDcfLQzsHvQCmfqHM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}