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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6d1ec2e67d19eb5b871b1f09b42144cfea33375bbcd4d9320cf55c545f63b7a' 
  AND token = '15q5pKrp/KkYXHKdTDgEL2DQyg+Od1AD2Xjx/AX/85o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}