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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c8b645fbd78b163086d63ab3bdd31be08428442f6742081527f8a4226970d6f' 
  AND token = 'AvX6MGW3WJnodk6C7U4ltNvysl9H4/ge38ob4X85DJ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}