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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e600c6816f2769f71b61a77631e58b29ad6e06d3b00b70ba1abb6aa406e8bc93' 
  AND token = 'fo5/UXV5n+lQBcIJbH9vQ/DaytXfJ2UM0OAQcVQBboQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}