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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea470eba88302532a5b8d0382c5df76562f55e0aa5842fc0049a877a0e00f264' 
  AND token = 'h3yUdxH+2chxDmECIdUmSN/bu08HUGE1eDprtCGOfLM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}