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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '79114d3bc0d3fbae5cc69ecd2cddadc12e7c1599476148c1ce170d0b63c99879' 
  AND token = 'qpDji+bS1VXQ1Hog+GR+iEq4B7I2PXykHaKzlR+bBWM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}