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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80bff3b5b2fb25ef79433648d06026b01c020732e0df232bb3b2ad8ae74d103d' 
  AND token = 'z72Iq0MFCih0wqum2G695j1kjhyoCgcEWTgCfiRdLMU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}