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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '486f9799556aaff436efd85341b4ce6eabec317ef83b424c9eba75e91ea036c2' 
  AND token = 'NBAC2KY4Nf3l/TtEjcyiX0FWFe7NTvfoAAqwrW6TBts=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}