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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2edb4e8c886d56b6f161f48a1dc6e577f389d8645fc090d80cb61ece6c90a50' 
  AND token = 'FBbRRNAdRe+mmGI8Vmn/wERLkO9eIbieo0QXF1b5wE4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}