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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e349c7a9af5a26bc2937e71920cf7d23b14da29a9dbfb4512937c38bc0b7ae2' 
  AND token = 'BqHRnCvNOPLaPrX1FuJbsnxbqxCLUCnQFiDUTaan0mY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}