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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8502c81a2583768b4c059d392b350c33ed521f83f9646aa4111d63a8b006f24e' 
  AND token = 'DRIXpS5qn7rZIIbKiI3HOi2EslEERnIwAWWgVFzzTqI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}