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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18959eccced923ae6feb1366bd64c6a6a1cc3d7832fa7d9a1ed5e1db56f0c487' 
  AND token = '4M6YS43oiGfypnoJ8uVqp1XQyiRVH7ZcdTTyGccjKHQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}