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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2b66ca2f071de3825e18404dac9ff6e6f4393b660dd50d33aa4f951f3222bb1' 
  AND token = 'shKwb0cbDceOhGkfx7qhyIuE+4pISCaO3hop9+b+wQA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}