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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b065155f2015f0e823a84fb9d7551d2c01ae1b86c99eed90fdc195e73bf3a56' 
  AND token = 'YpWPBUWoR2mMj24csfYHY/0IMG5rSsZuf0Ep23Oi5Sw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}