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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6346b1c6d673c7b58111e0e3ba786688c1eb8e69619c85a8c913ea003a1e0690' 
  AND token = 'p5dCl0QGcyKxHJzILX9MryI++Fafl2ZJ3Sb4yFYbN7k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}