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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '591fee4ea0f9a14295ea6f96b21236fb78551e60accf8a881a8dd519a445a603' 
  AND token = 'tvGp7erK3WmleqqgQG01wRDC1nt1h+YImodlB3LwRnE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}