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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e3d43cae5f188fb34fb76cb088830e8298a6054dde0ff424d75a06605a6786a' 
  AND token = 'LFR6QMFBSapkGqjudYe0+ILcT3xN9aasVhKFy2MijW8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}