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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54532419e194304061c3a4b2896aa9f339de19a8d7be222926383a19a2c1684c' 
  AND token = '5FEM8g9TtE1CIlLXf9EaVgiQTmHs0y/lCbn9csMOuw4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}