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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f22b8db1d1cd35d984562c1773c5c8842fa10306a917cbc921469d93df2fb513' 
  AND token = 'dgfttCDqAdz8ddorZvbbbtVw9bTjgzgOmoJj96u0pVQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}