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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd53c13520952087c7a7b4d65e6ec6264336c781cd2c291223de3ffd2d8a4ab34' 
  AND token = 'H1WPvv4u7KaehbSKCRvVzHQpffcAV2uFNRgnd+5LhQs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}