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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd375139a2ddf7ea5d6f9a68a6b031cb633291a25c9b39e01a21fa9dea9f162f5' 
  AND token = 'nyFmMJ1XgjiLYP6YMfaYgrmmkQlqtIuZYU/3z55TWqA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}