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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4a9b12a516c39e1c65c090e5f2ac38555d2d64c762107bd93c650e5e910f6eb' 
  AND token = 'zktVczqt8wzTj46WvkzhfMat16LUYvNScrOMXse3UZ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}