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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd497ecf4fa6c32b9013b5b10fe022ad47565efdcdcffc339f680a75d56ac2a53' 
  AND token = '2vKEwLMneW12ZGDjR9YMBIlDSLh33GoFZsd9kU+0J1Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}