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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce33494e37ca98fd761e183802d903e15a45223a15f9e736386920991e7efdcf' 
  AND token = 'UCss8nQp8gwS8DRPwn+P6ifuqhzIaygM9AYBJFLestg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}