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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d8a391195c4d361de218ccefb25bbc9b5b946ab5978dc26942dd03841b92844' 
  AND token = '2MRM8HDOC93yvrGsulOnh7IB0tTpA3iuO7RW5I0Y/Dk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}